Varlociraptor Versions Save

8.4.7 (2024-05-11)

Bug Fixes

• improved specificity of read position bias model by estimating the rate of the predominant read position from the ref supporting observations (#425) (eea6727)

8.4.6 (2024-03-27)

Bug Fixes

• fix bug during calculation of read position bias (#422) (33d98b6)
• fix decompression of CRAM files that rely on an external reference FASTA. Varlociraptor now uses the given reference FASTA for this decompression (#420) (75810c6)

8.4.5 (2024-02-21)

Bug Fixes

• fail if insert size standard deviation is zero, because that is unrealistic and causes numeric issues (#410) (cf6eead)

8.4.4 (2024-01-30)

Bug Fixes

• fix homopolymer identification (#407) (e99bf23)

8.4.3 (2024-01-22)

Bug Fixes

• fix invalid identification of homopolymer error (#405) (e1b66cc)

8.4.2 (2023-11-09)

Bug Fixes

• out of bounds error in estimation of third allele probability (#403) (37eafa4)

8.4.1 (2023-10-07)

Bug Fixes

• add flag for stating that candidate variants are atomic (in such cases, no realignment against SNVs and MNVs should happen because nearby indels can induce false positives if they are not considered in the realignment) (#400) (2e22c50)

8.4.0 (2023-09-19)

Features

• methylation candidates (#394) (d977058)

Bug Fixes

• fixed handling of allele frequency boundaries (avoiding NaN probabilities in some rare cases); fixed handling of upper reference bound when estimating probability of third allele (#398) (e255ff9)

Miscellaneous Chores

• trigger release 8.3.1 (2db869f)
• trigger release 8.4.0 (668cc49)

Features

• implement "true" formula terminal (#384) (fc45604)

Features

• warn on missing ANN records in mutational burden estimation (#376) (32006fb)

Bug Fixes

• Improved parameter estimation for (H)PHMM (#371) (508333e)