Gagneurlab Drop Versions Save

Pipeline to find aberrant events in RNA-Seq data, useful for diagnosis of rare disorders

1.3.4

1 week ago
  • fixes the FRASER version to 1.99.3 commit d6a422c to ensure reproducibility
  • fixes the OUTRIDER version to 1.20.1
  • fixes certain scripts affected by a snakemake update

1.3.3

1 year ago

Fixes a bug when compiling the aberrant splicing results.

1.3.2

1 year ago

Fixes issues with having only 1 internal sample. Simplifies the counting Summary html in the aberrant splicing module.

1.3.1

1 year ago
  • small bugfix in the Aberrant Splicing Counting Summary Script when providing only 1 external sample

1.3.0

1 year ago
  • Supports FRASER 2.0, an improved version that uses the Intron Jaccard Index as its single splice metric
  • Allows to provide lists of genes to test during FDR correction in addition to the transcriptome-wide FDR across all expressed genes

1.2.4

1 year ago

What's Changed

  • Bug Fixes in MAE
  • yieldSize and dnaRnaMatchCutoff config values
    • yieldSize: allows for memory consideration in VCF and BAM file processing
    • dnaRnaMatchCutoff: sets the threshold for MAE sample matching
  • Summary edits to aberrantSplicing

Full Changelog: https://github.com/gagneurlab/drop/compare/1.2.3...1.2.4

1.2.3

1 year ago

Full Changelog: https://github.com/gagneurlab/drop/compare/1.2.2...1.2.3

1.2.2

1 year ago

Fixes a bug in the aberrant expression module when external counts are not provided.

Full Changelog: https://github.com/gagneurlab/drop/compare/1.2.1...1.2.2

1.2.1

1 year ago

1.2.0

1 year ago

What's Changed

Addition of the rnaVariantCalling module and inclusion of external splice counts for the aberrantSplicing module

Full Changelog: https://github.com/gagneurlab/drop/compare/1.1.4...1.2.0